A concerning outbreak of the Bundibugyo virus species of Ebola has spread across the Democratic Republic of Congo (DRC) and Uganda, leading to a coordinated international health response. As of June 12, 2026, the Democratic Republic of Congo has reported a cumulative total of 676 confirmed cases, including 136 deaths. The Ituri province in the DRC remains the most heavily affected region, with 629 confirmed cases across 19 health zones. Cases have also been reported in North Kivu and South Kivu provinces. [3, 4, 7] In Uganda, a total of 19 confirmed cases, including two deaths, have been reported as of June 11, 2026. The cases in Uganda are epidemiologically linked to transmission originating in the DRC, with evidence of both imported infections and secondary transmission among contacts and healthcare workers. Notably, Uganda has not reported any new cases in the six days preceding this update. [4, 8]

The outbreak, first declared in the DRC on May 15, 2026, is particularly challenging due to the rare Bundibugyo virus strain, for which there is no existing vaccine or specific treatment, although promising candidates are under development. [5, 6] The situation is further complicated by a humanitarian crisis, remote and densely populated areas, insecurity, and significant population and trade movements within the affected regions. [5, 6]

The World Health Organization (WHO) declared the outbreak a public health emergency of international concern on May 16, 2026, prompting a scaled-up international response. [6, 9] The Africa Centres for Disease Control and Prevention (Africa CDC) and WHO have launched a joint continental preparedness and response plan, aiming to raise $518 million to support African countries in detecting and responding to the outbreak. [10] This plan complements national response efforts by the DRC and Uganda, focusing on emergency coordination, surveillance, laboratory testing, infection prevention and control, clinical care, community engagement, and cross-border preparedness. [10]

The United States has also committed significant resources, with the Department of State providing over $162 million in foreign assistance, including the establishment of dedicated Ebola response clinics and support for numerous health facilities for screening, transport, and treatment. [11] Humanitarian funding of $350 million has also been channeled through OCHA pooled funds to the DRC, South Sudan, and Uganda. [11]

Efforts are underway to strengthen surveillance, contact tracing, and laboratory diagnostic capacities to accelerate the analysis of suspected Ebola samples. [8] Community engagement is recognized as a critical component of the response, aiming to build trust and ensure community participation in containment efforts. [5, 8, 10]

While the outbreak is currently confined to the DRC and Uganda, the risk of cross-border transmission remains a concern, prompting enhanced screening and public health measures at points of entry. [9, 10]